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Giuseppe Domenico Scarlatti (26 October 1685 – 23 July 1757) was an Italian composer who spent much of his life in the service of the Portuguese and Spanish royal families. He is classified as a Baroque composer chronologically, although his music was influential in the development of the Classical style. Like his renowned father Alessandro Scarlatti he composed in a variety of musical forms although today he is known mainly for his 555 keyboard sonatas. Domenico Scarlatti was born in Naples,

Franklin Delano Roosevelt ( /ˈroʊzəvɛlt/ roh zə vɛlt or  /ˈroʊzəvəlt/ roh zə vəlt; January 30, 1882 – April 12, 1945), also known by his initials, FDR, was the 32nd President of the United States (1933–1945) and a central figure in world events during the mid 20th century, leading the United States during a time of worldwide economic crisis and world war. The only American president elected to more than two terms, he facilitated a durable coalition that realigned American politics for decades .

Ontario /ɒnˈtɛərioʊ/ is a province of Canada, located in east central Canada. It is Canada's most populous province/territory and fourth largest in total area. It is home to the nation's most populous city, Toronto, and the nation's capital, Ottawa. Ontario is bordered by Manitoba to the west, Hudson Bay to the north, Quebec to the east, and by the U.S. states of Minnesota, Michigan, New York, Ohio and Pennsylvania to the south. All but a small portion of Ontario's 2,700 km (1,677 mi) border

Estradiol (E2 or 17β estradiol, also oestradiol) is a sex hormone. Estradiol is abbreviated E2 as it has 2 hydroxyl groups in its molecular structure. Estrone has 1 (E1) and estriol has 3 (E3). Estradiol is about 10 times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect. Except during the early follicular phase of the menstrual cycle, its serum levels are somewhat higher than that of estrone during the reproductive years of the human female. Thus it is the